𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Impact of radioimmunoguided surgery®

✍ Scribed by Gregory J. La Valle; Aaron Chevinsky; Edward W. Martin JR.

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
378 KB
Volume
7
Category
Article
ISSN
8756-0437

No coin nor oath required. For personal study only.

✦ Synopsis

Radioimmunoguided surgery (RIGS@) is a technique employed to locate tumor deposits with the aid of intravenously injected, tumor-specific, radiolabeled monoclonal antibodies and a small gamma detecting device. The gamma detecting probe (GDP) is a small, portable unit which has the capacity to be used intraoperatively to survey the entire peritoneal surface for increased radioactivity indicative of targeted tumor tissue during abdominal exploration for colorectal cancer. Trials in humans have demonstrated the ability of this system to locate clinically nonpalpable tumor deposits in patients undergoing carcinoembryonic antigen second-look laparotomies. This feature may be of value in improving the definition of tumor location and extent as well as allowing a more thorough resection of tumor-bearing tissue to be performed and hopefully improving overall patient survival.

📜 SIMILAR VOLUMES

Radioimmunoguided surgery and intraopera
Radioimmunoguided surgery and intraoperative lung cancer staging
✍ Manuele Grazia; Alessandro Bini; Franco Stella; Daniela Pagani; Ruggero Bazzocch 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB 👁 2 views

Radioimmunoguided surgery (RIGS) has proven its worth, especially when used in primary, recurrent, and metastatic colon-rectum adenocarcinomas, and in liver metastases from other intestinal adenocarcinomas. Until now, RIGS has not been investigated for lung cancer surgery, chiefly because of problem

Role of radioimmunoguided surgery using
Role of radioimmunoguided surgery using Iodine-125-labeled B72.3 monoclonal antibody in gastric cancer surgery
✍ Enzo Lucisano; Sergio Bertoglio 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 26 KB

Uniform and accurate staging of gastric cancer is essential to predict prognosis and assess the effectiveness of treatment strategies. An appropriate amount of surgical resection of the primary tumor and lymph node dissection appears to be fundamental for such staging. In seven out of 10 patients wh

Use of radioimmunoguided surgery after i
Use of radioimmunoguided surgery after induction chemotherapy in locally advanced breast cancer
✍ Fausto Badellino; Sergio Bertoglio; Giuliano Mariani; Paolo Meszaros; Giuseppe C 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 47 KB 👁 2 views

Twenty-one patients with histologically proven locally advanced breast cancer (LABC) were treated with a combined modality approach based on primary chemotherapy and radical modified mastectomy followed by adjuvant chemotherapy. Surgery was performed by using radioimmunoguided surgery (RIGS) techniq