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Impact of mitochondrial regulation of apoptosis on the pathogenesis and treatment of HIV-1-induced immunodeficiency

✍ Scribed by Eric J. Buenz; Andrew D. Badley

Book ID
116751398
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
402 KB
Volume
4
Category
Article
ISSN
1567-7249

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## Abstract To characterize the molecular links between type‐1 autosomal dominant optic atrophy (ADOA) and OPA1 dysfunctions, the effects of pathogenic alleles of this dynamin on mitochondrial morphology and apoptosis were analyzed, either in fibroblasts from affected individuals, or in HeLa cells