Impact of MHC Class I Gene on Resistance to Murine AIDS
β Scribed by M. MAKINO; D. B. MURPHY; R. W. MELVOLD; J. W. HARTLEY; H. C. MORSE III
- Book ID
- 110861076
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 445 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0300-9475
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Studies of rabbit major histocompatibility complex proteins have suggested that rabbits express only a single class I antigen, in contrast to most mouse strains (H-2K, D, and L) and man (HLA-A, -B, and -C), which express three. To explore the significance and the molecular basis of this apparent spe
It has been claimed that class I MHC loci are homogenized within species by frequent events of interlocus genetic exchange ("concerted evolution"). Evidence for this process includes the fact that certain rat class I loci (including RT1.A) located centromeric to class II and class III are more simil