Twenty-one patients with malignant melanoma stage III and IV were treated by intradermal injections of MER--methanol extraction residue of Baccillus Calmette-GuΓ©rin (BCG). Twelve of the patients, all with active disease, received chemotherapy in addition. Tests of skin reactivity to recall antigens
β¦ LIBER β¦
Impact of KIR/HLA ligand combinations on immune responses in malignant melanoma
β Scribed by Elissaveta Naumova; Anastassia Mihaylova; Milena Ivanova; Snejina Mihailova
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 276 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0340-7004
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## Abstract Loss of HLA class I expression on tumor cells is a frequent event as an immune escape mechanism. Seven different altered HLA phenotypes have been defined in tumors. Various molecular mechanisms have been described as responsible for HLA class I loss. HLA class I expression alterations o