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Impact of interactions between normal and transformed epithelial cells and the relevance to cancer

โœ Scribed by Catherine Hogan

Publisher
Springer
Year
2011
Tongue
English
Weight
356 KB
Volume
69
Category
Article
ISSN
1420-682X

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A hierarchical model of epithelial cell generation is proposed, in which even in extreme old age mature epithelial cells in humans are only a limited number of cell divisions from the zygote (60}120). This contrasts with conventional models in which regularly cycling stem cells can be several thousa