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Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro

✍ Scribed by F. Ris; E. Hammar; D. Bosco; C. Pilloud; K. Maedler; M. Donath; J. Oberholzer; E. Zeender; P. Morel; D. Rouiller; P. Halban

Publisher
Springer
Year
2002
Tongue
English
Weight
133 KB
Volume
45
Category
Article
ISSN
0012-186X

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## Abstract A critical shortage of donor pancreata currently prevents the development of a universal cell‐based therapy for type I diabetes. The ex vivo expansion of insulin‐producing β‐cells offers a potential solution but is problematic due to the inherent tendency of these cells to transition in