Tenofovir is a new effective treatment option for patients with chronic hepatitis B, but could be potentially hampered by mutations in the hepatitis B virus (HBV) polymerase conferring drug resistance. Drug resistance may occur preferentially if long-term administration is required, for example, in
Impact of hepatitis B e antigen-suppressing mutations on the replication efficiency of entecavir-resistant hepatitis B virus strains
β Scribed by S. Amini-Bavil-Olyaee; U. Herbers; T. Luedde; C. Trautwein; F. Tacke
- Book ID
- 108886521
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 274 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1352-0504
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Hepatitis B e antigen (HBeAg) and antibody (anti-HBe) were studied by radioimmunoassay in consecutive series of 145 asymptomatic hepatitis B surface antigen (HBsAg) carriers, 389 patients with HBsAg-positive chronic liver disease and 194 patients with HBsAg-positive hepatocellular carcinoma, and com