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Impact of Genotyping Errors on Type I Error Rate of the Haplotype-Sharing Transmission/Disequilibrium Test (HS-TDT)

โœ Scribed by Michael Knapp; Tim Becker


Book ID
117854399
Publisher
American Society of Human Genetics
Year
2004
Tongue
English
Weight
67 KB
Volume
74
Category
Article
ISSN
0002-9297

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## Abstract Because most multipoint linkage analysis programs currently assume linkage equilibrium between markers when inferring parental haplotypes, ignoring linkage disequilibrium (LD) may inflate the Type I error rate. We investigated the effect of LD on the Type I error rate and power of nonpa