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Impact of genetic analysis on Parkinson's disease research

✍ Scribed by John Hardy


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
77 KB
Volume
18
Category
Article
ISSN
0885-3185

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✦ Synopsis


Genetic analysis is changing our view of Parkinson's disease: not only is it challenging the long-cherished views about the diagnosis of the disease, it is also starting to suggest a biochemical pathway to disease pathogenesis. These developments are reviewed in the context of three known (synuclein, parkin, and DJ-1) and one suspected (ubiquitin hydrolase) genes for the disease.


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