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Impact of functionalABCG2polymorphisms on the adverse effects of gefitinib in Japanese patients with non–small-cell lung cancer

✍ Scribed by Keiichi Akasaka; Takayuki Kaburagi; Shin’ichi Yasuda; Kyoko Ohmori; Kaori Abe; Hironori Sagara; Yoshihiko Ueda; Koshu Nagao; Johji Imura; Yasuo Imai

Publisher
Springer
Year
2009
Tongue
English
Weight
212 KB
Volume
66
Category
Article
ISSN
0344-5704

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## Abstract We investigated the relationships between genetic factors and clinical outcome in Japanese non‐small‐cell lung cancer (NSCLC) patients treated with gefitinib. Ninety‐eight NSCLC patients who had been treated with gefitinib, were screened for mutations in epidermal growth factor receptor