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Impact of fat and muscle in energy dispersive X-ray diffraction-based identification of heroin using multivariate data analysis

✍ Scribed by Wei Li; Fang Zhang; Daoyang Yu; Bai Sun; Minqiang Li; Jinhuai Liu


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
459 KB
Volume
25
Category
Article
ISSN
0886-9383

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✦ Synopsis


ABSTRACT

As for the detection of drug body packing, skin is a typical interference factor. In this paper, multivariate data analysis was proposed to analyze the impact of fat and muscle on heroin identification based on the profile of spectra of energy dispersive X‐ray diffraction. In the space of principal components, the results showed that different pure samples (heroin, muscle, fat) clustered in different areas, whereas the location of mixture samples moved between locations of pure samples. The impact of fat and muscle lies in moving the feature points between pure materials in the space of principal components. Furthermore, the model of heroin covered by fat and muscle of different thicknesses was set up, and a linear relationship was proven to be suitable. Our findings indicate that multivariate data analysis would be a promising method in the detection of drug body packing. Copyright © 2011 John Wiley & Sons, Ltd.