Impact of factor VIII deficiency on clotting factor utilization in the United States
β Scribed by Louis M. Aledort; Scott H. Goodnight; A. Vuaya Rao; Jan Schwarz; Deborah Whitehurst; Sandor S. Shapiro; Hemophilia Study Group
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 589 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0940-5437
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π SIMILAR VOLUMES
## Abstract ## Background Gene therapy for hemophilia A with adenoβassociated virus (AAV) vectors involves difficulties in the efficient expression of factor VIII (FVIII) and in antibody formation against transgeneβderived FVIII. ## Methods AAV8 vectors carrying the canine B domain deleted FVIII
**Summary.** The impact on the cost of care for haemophilia patients with inhibitors is not well defined. To quantify the effect on health care expenditures associated with inhibitors to factor VIII (FVIII) or FIX, we conducted a retrospective cohort study examining product use and outcomes in adult