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Impact of environmental and endogenous factors on endopolyploidization in angiosperms

✍ Scribed by Gabriele Jovtchev; Martin Barow; Armin Meister; Ingo Schubert

Book ID
113603122
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
306 KB
Volume
60
Category
Article
ISSN
0098-8472

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The polymorphic cytochrome P-450 DB1 (P-450 IID6) is responsible for the O-demethylation of codeine to morphine by human liver microsomes. The influence of P-450 DB1 variable activity on the bioactivation of codeine in vivo to morphine and on its analgesic effect was investigated in phenotyped healt