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Impact of diet-induced obesity in male mouse reproductive system: The role of advanced glycation end product-receptor for advanced glycation end product axis

✍ Scribed by Moschonas, D. P.; Piperi, C.; Korkolopoulou, P.; Levidou, G.; Kavantzas, N.; Trigka, E.-A.; Vlachos, I.; Arapostathi, C.; Perrea, D.; Mitropoulos, D.; Diamanti-Kandarakis, E.; Papavassiliou, A. G.


Book ID
124054909
Publisher
Royal Society of Medicine Press
Year
2014
Tongue
English
Weight
648 KB
Volume
239
Category
Article
ISSN
1535-3702

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Multiligand receptor for advanced glycation end products (RAGE) is expressed in a wide variety of tissues, including the liver. Interactions with its ligands lead to cellular activation and thus prolonged inflammation and apoptosis. RAGE also exists in a soluble, truncated isoform called soluble RAG