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Impact of CYP2C19 polymorphisms on the efficacy of clobazam therapy

โœ Scribed by Seo, Takayuki; Nagata, Rie; Ishitsu, Takateru; Murata, Tsukasa; Takaishi, Chisato; Hori, Masaharu; Nakagawa, Kazuko


Book ID
120010188
Publisher
Future Medicine
Year
2008
Tongue
English
Weight
298 KB
Volume
9
Category
Article
ISSN
1462-2416

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CYP2D6 polymorphisms and the impact on t
โœ Jacob N. Beverage; Tristan M. Sissung; Amy M. Sion; Romano Danesi; William D. Fi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 122 KB

The cytochrome P450 2D6 (CYP2D6) is an enzyme known to metabolize a variety of xenobiotics and drugs. Inter-individual variation in the metabolic capacity of this enzyme has been extensively studied and associations with genotype have been established. Genetic polymorphisms have been grouped as nonf