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Impact of Clock Gene Bmal1 Deficiency on Nutritionally Induced Obesity in Mice

✍ Scribed by Bianca Hemmeryckx; Uwe Himmelreich; Marc F. Hoylaerts; Henri R. Lijnen


Book ID
109970167
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
99 KB
Volume
19
Category
Article
ISSN
1930-7381

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## Background: Genetic background has a profound effect on inflammatory bowel disease. the gpx1 and gpx2 double knockout (gpx1/2-dko) mice on a mixed c57bl/6 (b6) and 129s1/svimj (129) background exhibit spontaneous ileocolitis. the dko mice on a b6 background have mild ileocolitis. we characterize