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Impact of Clinical Reverse Transcriptase Sequences on the Replication Capacity of HIV-1 Drug-Resistant Mutants

✍ Scribed by Carrie Dykes; Kora Fox; Amanda Lloyd; Michael Chiulli; Eugene Morse; Lisa M. Demeter


Book ID
112273563
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
208 KB
Volume
285
Category
Article
ISSN
0042-6822

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## Abstract An extended spectrum of HIV‐1 reverse‐transcriptase (RT) mutations in HAART‐treated patients has been recently described. To verify the possible association of previously unreported RT mutations with a decrease of phenotypic susceptibility to nucleoside (NRTIs) and non‐nucleoside (NNRTI