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Impact of chronic statin-pretreatment on myocardial damage as assessed by Cardiac Magnetic Resonance findings in patients with acute ST-elevation myocardial infarction

โœ Scribed by Georg Fuernau; Ingo Eitel; Steffen Desch; Suzanne de Waha; Gerhard Schuler; Holger Thiele


Publisher
BioMed Central
Year
2012
Tongue
English
Weight
68 KB
Volume
14
Category
Article
ISSN
1097-6647

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โœฆ Synopsis


Background

Recent data have demonstrated a lower mortality in acute ST-elevation myocardial infarction (STEMI) patients with previous treatment with statins, especially in patients with high risk profiles. Moreover, a significant reduction in enzymatic infarct size in non-STEMI patients could be observed. However, systematic data of the impact of chronic statin pre-treatment on myocardial damage and reperfusion injury assessed with the gold standard cardiac magnetic resonance imaging (CMR) are lacking.

The aim of our prospective study was therefore to assess the effects of a chronic statin pre-treatment on myocardial damage as assessed by CMR in patients with acute reperfused STEMI.

None.


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