✦ LIBER ✦

Impact of bilateral pallidal stimulation on DYT1-generalized dystonia in Japanese patients

✍ Scribed by Satoshi Goto; Kazumichi Yamada; Hideki Shimazu; Nagako Murase; Kazuhito Matsuzaki; Tetsuya Tamura; Shinji Nagahiro; Jun-Ichi Kuratsu; Ryuji Kaji

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 56 KB
Volume: 21
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.21021

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✦ Synopsis

Abstract

Early‐onset generalized dystonia attributable to a DYT1 gene mutation is a hyperkinetic movement disorder that responds poorly to pharmacotherapy. In this video brief, we show that continuous bilateral stimulation of the globus pallidus internus produced sustained and marked improvements in the motor symptoms and functional disabilities of Japanese patients with DYT1‐generalized dystonia. © 2006 Movement Disorder Society

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