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IMPACT OF ALLELIC VARIANTS OF SINGLE NUCLEOTIDE POLYMORPHISMUS (SNP) RS1018381 IN SCHIZOPHRENIA RISK-GENE DYSBINDIN 1 ON NEURAL CORRELATES OF WORKING MEMORY

✍ Scribed by Sören Krach; Axel Krug; Valentin Markov; Tony Stöcker; N. Jon Shah; Karl Zilles; Markus H Skowronek; Thomas Eggermann; Klaus Zerres; Frank Schneider; Markus M Nöthen; Marcella Rietschel; Tilo Kircher

Book ID: 119557119
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 74 KB
Volume: 102
Category: Article
ISSN: 0920-9964
DOI: 10.1016/s0920-9964(08)70297-4

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## Abstract Working memory (WM) dysfunction is a hallmark feature of schizophrenia. Functional imaging studies using WM tasks have documented both prefrontal hypo‐ and hyperactivation in schizophrenia. Schizophrenia is highly heritable, and it is unclear which susceptibility genes modulate WM and i