Impact of age on outcome of pediatric acute myeloid leukemia : A report from 2 institutions
β Scribed by Bassem I. Razzouk; Elihu Estey; Stanley Pounds; Shelly Lensing; Sherry Pierce; Mark Brandt; Jeffrey E. Rubnitz; Raul C. Ribeiro; Michael Rytting; Ching-Hon Pui; Hagop Kantarjian; Sima Jeha
- Book ID
- 102106827
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 147 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0008-543X
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Background. Acute myeloid leukemia (AML) is well-recognized as one of the most important second malignancies. We report the occurrence of secondary AML (sAML) in our institution. Procedure. From September 1987 to August 1996 we have observed sAML in 9 patients (median age 4 years), 5 of them previo
## Abstract Survivin, a member of the inhibitor of apoptosis protein family, is expressed in most human cancers, but undetectable in normal differentiated adult tissue __in vivo__. Because of this cancerβrelated expression, survivin is a promising target for cancer therapy. To determine the express