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Impact of a human CMP-sialic acid transporter on recombinant glycoprotein sialylation in glycoengineered insect cells

โœ Scribed by Mabashi-Asazuma, H.; Shi, X.; Geisler, C.; Kuo, C.-W.; Khoo, K.-H.; Jarvis, D. L.


Book ID
118246350
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
450 KB
Volume
23
Category
Article
ISSN
0959-6658

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Enhancing recombinant glycoprotein sialy
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## Abstract Glycosylation engineering strategies that are currently used to improve quality of recombinant glycoproteins involve the manipulation of glycosyltransferase and/or glycosidase expression. We explored the possibility that over expressing nucleotide sugar transporters, particularly the CM