๐”– Bobbio Scriptorium
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Immunotherapy of spontaneous metastatic lung cancer with tumor antigen-pulsed, interleukin-12 gene-modified dendritic cells

โœ Scribed by Ji-quan Chen; Qing-yu Xiu; Ze-min Yan; Wen-tong Luo


Book ID
107466674
Publisher
Chinese Anti-Cancer Association
Year
2003
Tongue
English
Weight
591 KB
Volume
15
Category
Article
ISSN
1000-9604

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The well-characterized P815 tumor model was used to optimize anti-tumor immunization approaches in mice. Tumor peptides derived from antigens P198 or P1A were targeted to antigen-presenting cells (APC) by ex vivo pulsing. Initial experiments with irradiated pulsed splenic dendritic cells (sDC) injec