✦ LIBER ✦

Immunotherapy of melanoma with BCG: Two fatalities following intralesional injection

✍ Scribed by Charles F. McKhann; Charles G. Hendrickson; Lynn E. Spitler; Audolfur Gunnarsson; D. Banerjee; William R. Nelson

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 551 KB
Volume: 35
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197502)35:2<514::aid-cncr2820350233>3.0.co;2-f

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✦ Synopsis

Two fatalities are reported following intralesional injection of BCG for immunotherapy of malignant melanoma. In both cases the terminal events were characterized by high fevers, major clotting defects, hypotension, and anuria, suggesting that the mechanism was hypersensitivity to BCG.