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Immunotherapy: A new paradigm for androgen-refractory prostate cancer

✍ Scribed by Kevin R. Loughlin

Book ID
116956372
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
45 KB
Volume
26
Category
Article
ISSN
1078-1439

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## Abstract The emergence of mutations in the androgen receptor (__AR__) gene is a recurrent event during progression of prostate cancer (PCa) on androgen ablation therapy. In this study, we show that nonsense mutations that lead to carboxyl‐terminal end truncated ARs are found at high frequency in