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Immunosuppressors Inhibit Voltage-Gated Potassium Channels in Human Peripheral Blood Lymphocytes

✍ Scribed by György Panyi; Rezső Gáspár; Zoltán Krasznai; Jan J. ter Horst; Marcel Ameloot; Adorján Aszalós; Paul Steels; Sándor Damjanovich

Book ID
115578321
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
94 KB
Volume
221
Category
Article
ISSN
0006-291X

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Endogenous voltage-gated potassium currents were investigated in human embryonic kidney (HEK293) and Chinese hamster ovary (CHO) cells using wholecell voltage clamp recording. Depolarizing voltage steps from ؊70 mV triggered an outwardly rectified current in nontransfected HEK293 cells. This current