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Immunosuppressive effects of Pseudomonas aeruginosa exotoxin A on human B-lymphocytes

โœ Scribed by Dominique Raymond Vidal; Pierre Garrone; Jacques Banchereau


Book ID
116073907
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
466 KB
Volume
31
Category
Article
ISSN
0041-0101

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Pseudomonas aeruginosa exotoxin A is a representative of a class of enzymes, the mono-ADP-ribosyl transferases, which catalyze the covalent transfer of an ADP-ribose moiety of NAD+ to a target substrate. Availability of the three-dimensional structure of exotoxin A provides the opportunity for mappi