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Immunosuppressive effects of a Kv1.3 inhibitor

✍ Scribed by Kashmira Shah; J Tom Blake; Christopher Huang; Paul Fischer; Gloria C Koo

Book ID: 114008246
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 346 KB
Volume: 221
Category: Article
ISSN: 0008-8749
DOI: 10.1016/s0008-8749(03)00063-7

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## Abstract The voltage‐gated Kv1.3 and the calcium‐activated KCa3.1 potassium channel modulate many calcium‐dependent cellular processes in immune cells, including T‐cell activation and proliferation and have therefore been proposed as novel therapeutic targets for immunomodulation. Kv1.3 is highl