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Immunosuppression Increases JC Polyomavirus Large T Antigen DNA Load in the Brains of Patients Without Progressive Multifocal Leukoencephalopathy

โœ Scribed by Bayliss, J.; Karasoulos, T.; McLean, C. A.


Book ID
121410137
Publisher
University of Chicago Press
Year
2012
Tongue
English
Weight
120 KB
Volume
207
Category
Article
ISSN
0022-1899

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## Abstract Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, which is thought to be a result of the reactivation of JC virus (JCV), a human polyomavirus. The disease occurs in individuals with immunosuppression and in recent years there has