Routine use of rabbit antithymocyte globulin (RATG) induction therapy remains controversial in pediatric liver transplantation. We reviewed our experience of 18 cadaveric liver transplants in 18 children over a span of 2 years. All patients received the same immunosuppression: perioperative steroid
Immunosuppression in pediatric liver transplantation: Are little people different?
β Scribed by Anil Dhawan
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 101 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1527-6465
- DOI
- 10.1002/lt.22422
No coin nor oath required. For personal study only.
β¦ Synopsis
The pediatric population has many physiological differences that can significantly alter the pharmacokinetic and pharmacogenomic disposition in terms of Abbreviations: EBV, Epstein-Barr virus; LT, liver transplantation; MMF, mycophenolate mofetil.
Potential conflict of interest: Unrestricted educational grants from Roche, Astellas, Novartis and Wyeth laboratories.
π SIMILAR VOLUMES
Corticosteroid-free immunosuppression (IS) may be potentially beneficial for transplanted patients, particularly children. The purpose of this study was to evaluate the efficacy and cost of such strategy in primary pediatric liver transplantation (LT). Fifty pediatric LT recipients were prospectivel
## Background: Regulatory T-cells (Treg) are natural suppressors of autoimmunity. Previous studies indicate that immunosuppressive drugs, especially calcineurin-inhibitors, may interfere with Treg homeostasis. Inflammatory bowel disease (IBD) can relapse or develop de novo after liver transplantati