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Immunoregulatory function of PIR-A/B+DCs in the inflammatory responses of dextran sodium sulfate-induced colitis

✍ Scribed by Kurishima, Akiko; Inaba, Muneo; Sakaguchi, Yutaku; Fukui, Toshiro; Uchida, Kazushige; Nishio, Akiyoshi; Nomura, Shosaku; Okazaki, Kazuichi

Book ID: 125348987
Publisher: Springer Japan
Year: 2013
Tongue: English
Weight: 734 KB
Volume: 49
Category: Article
ISSN: 0944-1174
DOI: 10.1007/s00535-013-0879-x

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Background: Dextran sodium sulfate (DSS) is used to induce murine colitis. Although the exact mechanism by which DSS administration causes disease is unknown, evidence suggests that the resident bacteria play a role in the development of murine DSS colitis, analogous to their role in human inflammat