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Immunoregulatory Activity, Biochemistry, and Phylogeny of Ovine Uterine Serpin

✍ Scribed by MORGAN R. PELTIER; PETER J. HANSEN

Book ID
118115845
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
109 KB
Volume
45
Category
Article
ISSN
8755-8920

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## Background Uterine serpins are members of the serine proteinase inhibitor superfamily. Like some other serpins, these proteins do not appear to be functional proteinase inhibitors. The most studied member of the group, ovine uterine serpin (OvUS), inhibits proliferation of several cell types inc

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## Abstract The hormonal‐regulated serpin, ovine uterine serpin (OvUS), also called uterine milk protein (UTMP), inhibits proliferation of lymphocytes and prostate cancer (PC‐3) cells by blocking cell‐cycle progression. The present aim was to identify cell‐cycle‐related genes regulated by OvUS in P