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Immunoregulation by leukotrienes and other lipoxygenase metabolites

✍ Scribed by Marek Rola-Pleszczynski

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
620 KB
Volume
6
Category
Article
ISSN
0167-5699

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Oxidized leukotrienes: Synthesis of 20-O
Oxidized leukotrienes: Synthesis of 20-OH and 20-COOH LTD4. Possible metabolites in the lipoxygenase pathway
✍ Julian Adams; Suzanne Milette; Joshua Rokach; Robert Zamboni πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 French βš– 209 KB

Leukotriene LTD4 analogs 20-OH LTD4 16 and ZO-COOH LTD4 17 were synthesized. These ti-oxidative derivatives are possible metΓ£601ites of the natural product. The leukotrienes LTC4, LTD4 and LTE4, also known as SRS-A (slow reacting substance of anaphalaxis) are al1 potent spasmogens, producing smooth