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Immunoquantitation of aldose reductase in human tissues

✍ Scribed by Charles E. Grimshaw; Eric J. Mathur


Book ID
102987396
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
922 KB
Volume
176
Category
Article
ISSN
0003-2697

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Aldose reductase (ALR2) has received considerable attention due to its possible link to long-term diabetic complications. Although crystal structures and kinetic data reveal important aspects of the reaction mechanism, details of the catalytic step are still unclear. In this paper a computer simulat