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Immunophenotypic Aberrations, DNA Content, and Cell Cycle Analysis of Plasma Cells in Patients with Myeloma and Monoclonal Gammopathies

✍ Scribed by Margarida Lima; Maria dos Anjos Teixeira; Sónia Fonseca; Cristina Gonçalves; Marisol Guerra; Maria Luı́s Queirós; Ana Helena Santos; António Coutinho; Luciana Pinho; Lucı́lia Marques; Manuel Cunha; Pinto Ribeiro; Luciana Xavier; Hermı́nia Vieira; Pureza Pinto; Benvindo Justiça


Book ID
115590073
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
278 KB
Volume
26
Category
Article
ISSN
1079-9796

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## Abstract ## BACKGROUND Monoclonal gammopathy of undetermined significance (MGUS) is a clonal plasma cell (PC) disorder usually characterized by a benign clinical course. However, in approximately 25% of patients, the disorder has been found to evolve into a multiple myeloma (MM). The mechanism