Immunophenotype and clinical characteristics of CD45-negative and CD45-positive childhood acute lymphoblastic leukemia
β Scribed by R. Ratei; C. Sperling; L. Karawajew; G. Schott; M. Schrappe; J. Harbott; H. Riehm; W.-D. Ludwig
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 324 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0939-5555
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D45 is the major transmembrane tyrosine phosphatase of the immune system and is highly expressed by all hematopoietic cells 1 . The best described role for CD45 is in antigen receptor signal transduction. In this case, the phosphatase activity of CD45 appears to be required for activation of Src-fam
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