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Immunopharmacological profile of new antirheumatic drug flobufen

✍ Scribed by J. Grimová; J. Lašťovička; A. Brejcha


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
85 KB
Volume
10
Category
Article
ISSN
0192-0561

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The present study was an attempt to elucidate the relationship between stereoselective pharmacokinetics and protein binding of KE-298 and its active metabolites, deacetyl-KE-298 (M-1) and S-methyl-KE-298 (M-2). Metabolic chiral inversion was also investigated. The levels of unchanged KE-298 in plasm