Immunopathogenesis of acute graft-versus-host disease: implications for novel preventive and therapeutic strategies
✍ Scribed by Robert Zeiser; Reinhard Marks; Hartmut Bertz; Jürgen Finke
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 240 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0939-5555
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Graft-versus-host disease (GVHD) after liver transplantation is rare but associated with a very high mortality (over 85%). Most treatments focus on increasing immunosuppression, addition of antibody preparations such as OKT3 and antithymocyte globulin to eliminate the donor lymphocytes, and supporti
CHOP, COP plui doxorubicin. ,'According to NCI criteria (Cheson el al. 151). (PD) was registered in one patient. Median time to disease progression for patients in PR or SD was 9 months (range, 1-14 months) (Table I). The results of the prehent study, although based on a small number of patients,