Immunomodulatory effects of systemic low-dose recombinant interleukin-2 and lymphokine-activated killer cells in humans
โ Scribed by Timothy J. Eberlein; Mary L. Rodrick; Anthony F. Massaro; Sung-Eun Jung; John A. Mannick; Deric D. Schoof
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 799 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Using a 4-h 51Cr release assay, we observed that thymocytes from Fischer strain rats incubated with recombinant human interleukin-2 (rhIL-2) developed cytotoxicity to YAC-1 lymphoma, 9L-glioma, and B-16 melanoma cells (effector/target ratio = 25/1). Induction of the lymphokine-activated killer (LAK)
Ten patients with hepatocellular carcinoma, three of whom had pulmonary metastasis, were treated with adoptive immunotherapy using autologous lymphokineactivated killer cells plus recombinant interleukin 2. Patients received 16 pg per day of recombinant interleukin 2 consecutively (for 14 to 64 days