Immunomodulatory effects of diclofenac in leukocytes through the targeting of Kv1.3 voltage-dependent potassium channels
✍ Scribed by Núria Villalonga; Miren David; Joanna Bielańska; Teresa González; David Parra; Concepció Soler; Núria Comes; Carmen Valenzuela; Antonio Felipe
- Book ID
- 113489240
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 689 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0006-2952
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## Abstract The present study traces the development of a voltage‐dependent potassium channel protein (Kv3.1) in the avian homologue of the cochlear nucleus, in the cochleovestibular ganglion, and in the otic epithelium from early developmental stages until near hatching. Immunohistochemistry with
## Abstract Kv3.1, a voltage‐dependent potassium channel, has two forms, ‐a and ‐b, which differ in expression during development and at the onset of function in the auditory system. To determine whether cochlear nerve input could affect the expression of these two forms, cultures of the developing