Statins amplify TLR-induced responses in
β
CΓ©line Van Der Putten; Hedwich F. Kuipers; Ella A. Zuiderwijk-Sick; Linda Van St
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Article
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2011
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John Wiley and Sons
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English
β 706 KB
## Abstract Statins inhibit the endogenous intracellular mevalonate pathway and exposure to statins affects innate and adaptive immune responses. Different statins are currently under evaluation as (co)therapy in neuroβinflammatory diseases like multiple sclerosis. However, there are important disc