BackgroundlAims: A double-blind, placebo-controlled trial of ursodeoxycholic acid (UDCA) was conducted in 180 patients with primary biliary cirrhosis (PBC) to define the efficacy and safety of UDCA Efficacy was assessed by time to treatment failure defined as death; liver transplantation; histologic
Immunomodulating effect of ursodeoxycholic acid therapy in patients with primary biliary cirrhosis
✍ Scribed by D. Kürktschiev; S. Subat; D. Adler; K.-U. Schentke
- Book ID
- 118566252
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 249 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0168-8278
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📜 SIMILAR VOLUMES
We have previously shown in a 2-yr controlled trial that hypercholesterolemia, frequent in primary biliary cirrhosis, is lowered by ursodeoxycholic acid (13 to 15 mg daily). To further investigate this effect, we analyzed the influence of long-term ursodeoxycholic acid administration on serum lipids
Bile acid composition in fasting duodenal bile was assessed at entry and at 2 years in patients with primary biliary cirrhosis (PBC) enrolled in a randomized, doubleblind, placebo-controlled trial of ursodeoxycholic acid (UDCA) (10-12 mg/kg/d) taken as a single bedtime dose. Specimens were analyzed