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Immunomodulating and articular protecting activities of a new anti-rheumatic drug, TAK-603

✍ Scribed by Yoshikazu Ohta; Shigeru Fukuda; Atsuo Baba; Hirofumi Nagai; Ryoichi Tsukuda; Takashi Sohda; Haruhiko Makino


Book ID
103571758
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
733 KB
Volume
34
Category
Article
ISSN
0162-3109

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Stereoselective pharmacokinetics of [14C
✍ Hideo Yoshida; Yoshiro Kohno; Hiromi Endo; Masatoshi Hasegawa; Toshio Suwa πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 540 KB

The stereoselective pharmacokinetics of two enantiomers of [14C]-labeled -(4-methylphenyl)-4-oxobutanonic acid] were investigated in rats. The blood levels of radioactivity after the oral administration of (+)-(S)-[14C]KE-298 were higher than that for (-)-(R)-[14C]KE-298; the AUC of the former was a