Immunology: an introductory textbook

✍ Scribed by Sharma, Anil K

• Publisher: Pan Stanford Publishing;CRC
• Year: 2019
• Tongue: English
• Leaves: 261
• Category: Library

✦ Synopsis

Immunology has emerged as a key component of the curricula of graduate and postgraduate courses in biotechnology, microbiology, biochemistry, bioinformatics, and other interdisciplinary fields of biology, including zoology, veterinary science, and medicine. As a basic introductory textbook on one of the fastest-moving and most challenging areas of immunological science, this book contains the most recent information about immunologic mechanisms and their importance, along with various molecular techniques employed in immunology. The short and concise text helps make the structures, processes, and interactions of the immune system easily comprehensible. The book includes chapters on immunoinformatics as well as the immune system of the brain, rarely found in any of the immunology books published so far. Many diverse and interesting aspects of the advances in immunology have also been covered, including tumor immunology and immunodeficiency disorders. The easy-to-understand concepts presented in the textbook make it an ideal companion for learners preparing for competitive and other examinations. Undergraduate, postgraduate, and PhD students, people from the industry and academia, and research scholars will immensely benefit from it.  Read more...

Abstract: Immunology has emerged as a key component of the curricula of graduate and postgraduate courses in biotechnology, microbiology, biochemistry, bioinformatics, and other interdisciplinary fields of biology, including zoology, veterinary science, and medicine. As a basic introductory textbook on one of the fastest-moving and most challenging areas of immunological science, this book contains the most recent information about immunologic mechanisms and their importance, along with various molecular techniques employed in immunology. The short and concise text helps make the structures, processes, and interactions of the immune system easily comprehensible. The book includes chapters on immunoinformatics as well as the immune system of the brain, rarely found in any of the immunology books published so far. Many diverse and interesting aspects of the advances in immunology have also been covered, including tumor immunology and immunodeficiency disorders. The easy-to-understand concepts presented in the textbook make it an ideal companion for learners preparing for competitive and other examinations. Undergraduate, postgraduate, and PhD students, people from the industry and academia, and research scholars will immensely benefit from it

✦ Table of Contents

Content: Cover
Half Title
Title Page
Copyright Page
Table of Contents
Preface
1: Introduction to lmmunology
1.1 Historical Attributes
1.2 lmmunological Responses and Effectors
1.2.1 lnnate and Adaptive lmmunity
1.2.1.1 lnnate immunity
1.2.1.2 Adaptive immunity
1.3 Summary
2: lmmunity
2.1 Basic Concept of lmmunity
2.2 Historical Background of Immune Responses
2.3 Cell-Mediated Immune Responses
2.4 Processing of Endogenous Antigens: Cytosolic Pathway
2.5 Processing of Endogenous Antigens: Endocytic Pathway
2.6 Humoral Immunity
2.7 Activation of B-Cells 2.8 Humoral Response to T-Dependent Antigens2.9 Humoral Response to T-lndependent Antigens
3: Proteins of the Immune System
3.1 Antimicrobial Peptide
3.2 Pattern Recognition Receptor
3.3 Toll-Like Receptors
3.4 NOD Protein
3.5 Acute Phase Proteins
3.6 Interferon
3.7 Complement System
3.7.1 Function of Complement System
3.7.2 Complement Nomenclature
3.8 Activation of Complement Pathways
3.9 Classical Pathway of the Complement System
3.10 Lectin Pathway
3.11 Alternative Pathway
3.12 Small Fragments of the Complement Protein Initiates Local Inflammatory Response 3.13 Membrane Attack Complex (MAC) or Lytic Pathway3.14 Regulation of Complement Protein
3.15 Summary
4: Major Histocompatibility Complex (MHC): Recent Trends and Relevance from lmmunological Perspective
4.1 Introduction
4.2 Nomenclature of HLA Antigens
4.3 Frequency of Different HLA Alleles
4.4 Molecular and Genetics Basis of MHC Polymorphisms
4.4.1 Inheritance
4.4.2 Expression
4.5 MHC Molecules: Structure and Genetics
4.5.1 MHC Class I vs. MHC Class Il
4.5.1.1 MHC Class I
4.5.1.2 MHC Class Il
4.6 Role of MHC in Immune Response
4.6.1 The Mixed Lymphocyte Reaction 4.6.2 Antigen Processing and Presentation4.6.3 Sorne Points about MHC Class I and Class Il /TCR
4.7 Antigen Processing and Presentation
4.8 Langerhans Cells as APC
4.9 Antigen Processing and Presentation by Class Il (Exogenous/Endocytic) Pathway
4.10 Antigen Processing and Presentation by Class I (Endogenous/Cytosolic) Pathway
4.11 Significance of MHC-Peptide Presentation
4.12 Clonal Selection of T-cells
4.13 Generation of Cytotoxic T-Cells
4.14 Immune Response Genes
4.15 Complement Factor Genes
4.16 Nonimmunologic Functions of MHC Genes 4.17 Disease and the Major Histocompatibility Complex5: Immune System of the Brain
5.1 Introduction
5.2 Microglia
5.3 Astrocytes
5.4 Toll-Like Receptors
5.5 Pro-lnflammatory Cytokines
5.6 Summary
6: An Overview of lmmunodeficiency Disorders
6.1 Introduction
6.2 Primary lmmunodeficiency Diseases
6.3 Classification of Primary lmmunodeficiency
6.3.1 Severe Combined lmmunodeficiency
6.3.1.1 X-linked recessive severe combined immunodeficiency
6.3.1.2 Adenosine deaminase deficiency
6.3.2 Well-Defined Syndromes with lmmunodeficiency

✦ Subjects

Immunology;HEALTH & FITNESS / Diseases / General;MEDICAL / Clinical Medicine;MEDICAL / Diseases;MEDICAL / Evidence-Based Medicine;MEDICAL / Internal Medicine;MEDICAL / Immunology;MEDICAL / Pharmacology;SCIENCE / Life Sciences / Biology / Microbiology