Immunological studies in ataxia-telangiectasia
✍ Scribed by ÖZden Kiran; Kalbiye Yalaz; Kutay Taysi; Burhan Say
- Book ID
- 119838111
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 292 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Two of three brothers with the classical signs of ataxia telangiectasia were investigated for their immunological disorders at the ages of 13 and 16 years, respectively. The elder brother also suffers from autoimmune hemolytic anemia, a complication which has not yet been described in the course of
This article summarizes the genetics and clinical features of ataxia telangiectasia (AT) and then reviews recent cytogenetic, cellular, and biochemical studies which support the hypothesis that a defect in DNA repair is responsible for the various manifestations of the disease. The biochemical evide