immunological response of the newborn to nonfatal Coxsackie B-4 virus infection
β Scribed by O. Sieber; V. Fulginiti; D. Pearlman
- Book ID
- 118534587
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- English
- Weight
- 68 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1097-6833
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## Abstract The pathology of Coxsackie virus B4 (CVB4) infection in a murine model was investigated by in situ hybridization using a biotinylated cDNA probe derived from CVB4. During the acute phase of infection virus RNA sequences were detected in the exocrine pancreas of 60% of mice infected with
Type I diabetes mellitus results from the autoimmune destruction of insulin producing beta cells in the pancreas. Certain viral infections, especially those caused by coxsackie B viruses and related enteroviruses, have been associated with the development of type I diabetes. The sequence homology be