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Immunological Defence against Preneoplastic Stages of Diethylnitrosamine Induced Carcinomas in Rat Liver

✍ Scribed by FRIEDRICH-FREKSA, H.; HOFFMANN, M.

Book ID: 109668003
Publisher: Nature Publishing Group
Year: 1969
Tongue: English
Weight: 309 KB
Volume: 223
Category: Article
ISSN: 0028-0836
DOI: 10.1038/2231162a0

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## Abstract To clarify the sequential changes in pRB and __p16__ during different stages of hepatocarcinogenesis such as fibrosis, cirrhosis, hepatocellular adenoma (HCA), and hepatocellular carcinoma (HCC), male Fischer 344 rats were singly injected with diethylnitrosamine (DEN), immediately follo