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Immunological aspects of progeria (Hutchinson-Gilford syndrome) in a 15-month-old child

✍ Scribed by M. Harjaček; D. Batinić; V. Sarnavka; B. Užarević; D. Mardešić; M. Marušić


Publisher
Springer
Year
1990
Tongue
English
Weight
326 KB
Volume
150
Category
Article
ISSN
0340-6997

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Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder normally caused by a spontaneous heterozygous mutation in the LMNA gene that codes for the nuclear lamina protein lamin A. Several enzymes are involved in the processing of its precursor, prelamin A, to the mature lamin A