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Immunological and Regulatory Functions of Uninfected and Virus Infected Immature and Mature Subtypes of Dendritic Cells – a Review

✍ Scribed by Yechiel Becker

Book ID
110437197
Publisher
Springer
Year
2003
Tongue
English
Weight
133 KB
Volume
26
Category
Article
ISSN
0920-8569

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## Abstract Herpes simplex virus (HSV) can perturb the function of dendritic cells (DC). The underlying mechanisms are not defined. In the present study we demonstrate that HSV induces a substantial number of immature DC to undergo apoptosis by a mechanism involving caspase‐8. We found strongly enh