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Immunological and molecular detection of tumor contamination in leukapheresis products from children with disseminated neuroblastoma: implication for evaluation of tumor cell depletion after CD34 selection

✍ Scribed by Tchirkov, A; Kanold, J; Combaret, V; Philip, I; Kwiatkowski, F; Malet, P; Deméocq, F

Book ID: 110012105
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 28 KB
Volume: 24
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bmt.1701865

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## Background: Autologous peripheral blood stem cell (pbscs) are frequently used to reconstitute hematopoiesis following administration of megatherapy in children with advanced stage iv neuroblastoma. some centers prefer the use of autografts enriched for cd34+ progenitor cells because the positive